Mental status examination
| Mental status examination |
| Intervention |
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The
mental status examination in the USA or
mental state examination in the rest of the world, abbreviated
MSE, is an important part of the clinical
assessment process in
psychiatric practice. It is a structured way of observing and describing a
patient's current state of
mind,
under the domains of appearance, attitude, behavior, mood and affect,
speech, thought process, thought content, perception, cognition, insight
and judgment.
[1] There are some minor variations in the subdivision of the MSE and the sequence and names of MSE domains.
The purpose of the MSE is to obtain a comprehensive cross-sectional
description of the patient's mental state, which, when combined with the
biographical and historical information of the
psychiatric history, allows the clinician to make an accurate
diagnosis and
formulation, which are required for coherent treatment planning.
The data are collected through a combination of direct and indirect
means: unstructured observation while obtaining the biographical and
social information, focused questions about current symptoms, and
formalised
psychological tests.
[2]
The MSE is not to be confused with the
mini-mental state examination (MMSE), which is a brief neuro-psychological
screening test for
dementia.
The mini-mental state examination (MMSE) is a popular screening tool
used to determine cognitive functioning. The MMSE is a reliable
measurement containing thirty questions that are used to test basic
cognitive functions such as attention, language production, orientation,
language comprehension, and immediate memory. The average time it takes
to complete the MMSE is five to ten minutes. People with normal
cognitive functioning usually score high on the measurement, ranging
from 27 to 30. The instrument is accurate in determining Alzheimer's
disease and other forms of dementia in elderly populations.
[3]
Theoretical foundations
The MSE derives from an approach to
psychiatry known as descriptive psychopathology
[5] or descriptive
phenomenology[6] which developed from the work of the philosopher and psychiatrist
Karl Jaspers.
[7]
From Jaspers' perspective it was assumed that the only way to
comprehend a patient's experience is through his or her own description
(through an approach of
empathic and non-theoretical enquiry), as distinct from an interpretive or
psychoanalytic
approach which assumes the analyst might understand experiences or
processes of which the patient is unaware, such as defense mechanisms or
unconscious drives.
In practice, the MSE is a blend of empathic descriptive phenomenology and
empirical clinical observation. It has been argued that the term
phenomenology has become corrupted in clinical psychiatry: current usage, as a set of supposedly
objective descriptions of a psychiatric patient (a synonym for
signs and
symptoms), is incompatible with the original meaning which was concerned with comprehending a patient's
subjective experience.
[8][9]
Application
The mental status examination is a core skill of psychiatrists,
psychologists,Occupational therapist, physician assistants, nurse
practitioners and other qualified mental health personnel. It is a key
part of the initial psychiatric assessment in an
out-patient or
psychiatric hospital
setting. It is a systematic collection of data based on observation of
the patient's behavior while the patient is in the clinician's view
during the interview. The purpose is to obtain evidence of symptoms and
signs of mental disorders, including danger to self and others, that are
present at the time of the interview. Further, information on the
patient's insight, judgment, and capacity for abstract reasoning is used
to inform decisions about treatment strategy and the choice of an
appropriate treatment setting.
[10]
It is carried out in the manner of an informal enquiry, using a
combination of open and closed questions, supplemented by structured
tests to assess cognition.
[11] The MSE can also be considered part of the comprehensive
physical examination performed by
physicians and nurses although it may be performed in a cursory and abbreviated way in non-mental-health settings.
[12] Information is usually recorded as free-form text using the standard headings,
[13] but brief MSE checklists are available for use in emergency situations, for example by
paramedics or
emergency department staff.
[14][15]
The information obtained in the MSE is used, together with the
biographical and social information of the psychiatric history, to
generate a diagnosis, a psychiatric formulation and a treatment plan.
Domains
Appearance
Clinicians assess the physical aspects such as the appearance of a
patient, including apparent age, height, weight, and manner of dress and
grooming. Colorful or bizarre clothing might suggest
mania, while unkempt, dirty clothes might suggest
schizophrenia or
depression.
If the patient appears much older than his or her chronological age
this can suggest chronic poor self-care or ill-health. Clothing and
accessories of a particular subculture,
body modifications, or clothing not typical of the patient's gender, might give clues to
personality. Observations of physical appearance might include the physical features of
alcoholism or
drug abuse, such as signs of
malnutrition, nicotine stains, dental erosion, a rash around the mouth from
inhalant abuse, or needle track marks from intravenous drug abuse. Observations can also include any odor which might suggest poor personal
hygiene due to extreme self-neglect, or
alcohol intoxication.
[16]Gelder,
Mayou & Geddes (2005) tells us to look out for weight loss. This
could signify a depressive disorder, physical illness, anorexia nervosa
or chronic anxiety.
Attitude
Attitude, also known as
rapport,
[17]
refers to the patient's approach to the interview process and the
interaction with the examiner. The patient's attitude may be described
for example as cooperative, uncooperative, hostile, guarded, suspicious
or
regressed.
The most subjective element of the mental status examination, attitude
depends on the interview situation, the skill and behaviour of the
clinician, and the pre-existing relationship between the clinician and
the patient. However, attitude is important for the clinician's
evaluation of the quality of information obtained during the assessment.
[18]
Behavior
Abnormalities of behavior, also called abnormalities of activity,
[19]
include observations of specific abnormal movements, as well as more
general observations of the patient's level of activity and arousal, and
observations of the patient's
eye contact and
gait. Abnormal movements, for example
choreiform,
athetoid or
choreoathetoid movements may indicate a
neurological disorder. A
tremor or
dystonia may indicate a neurological condition or the side effects of
antipsychotic medication. The patient may have
tics (involuntary but quasi-purposeful movements or vocalizations) which may be a symptom of
Tourette's syndrome. There are a range of abnormalities of movement which are typical of
catatonia, such as
echopraxia,
catalepsy,
waxy flexibility and
paratonia (or
gegenhalten[20]).
Stereotypies
(repetitive purposeless movements such a rocking or head banging) or
mannerisms (repetitive quasi-purposeful abnormal movements such as a
gesture or abnormal gait) may be a feature of chronic schizophrenia or
autism. More global behavioural abnormalities may be noted, such as an increase in arousal and movement (described as
psychomotor agitation or
hyperactivity) which might reflect
mania or
delirium. An inability to sit still might represent
akathisia, a side effect of antipsychotic medication. Similarly a global decrease in arousal and movement (described as
psychomotor retardation,
akinesia or
stupor) might indicate depression or a medical condition such as
Parkinson's disease,
dementia
or delirium. The examiner would also comment on eye movements
(repeatedly glancing to one side can suggest that the patient is
experiencing hallucinations), and the quality of eye contact (which can
provide clues to the patient's emotional state). Lack of eye contact may
suggest autism.
[21][22][23]
Mood and affect
The distinction between
mood and
affect in the MSE is subject to some disagreement. For example Trzepacz and Baker (1993)
[24]
describe affect as "the external and dynamic manifestations of a
person's internal emotional state" and mood as "a person's predominant
internal state at any one time", whereas Sims (1995)
[25]
refers to affect as "differentiated specific feelings" and mood as "a
more prolonged state or disposition". This article will use the Trzepacz
and Baker (1993) definitions, with mood regarded as a current
subjective state as described by the patient, and affect as the
examiner's inferences of the quality of the patient's emotional state
based on objective observation.
[26]
Mood is described using the patient's own words, and can also be described in summary terms such as neutral,
euthymic,
dysphoric,
euphoric,
angry,
anxious or
apathetic.
Alexithymic
individuals may be unable to describe their subjective mood state. An
individual who is unable to experience any pleasure may be suffering
from
anhedonia.
Affect is described by labelling the apparent emotion conveyed
by the person's nonverbal behavior (anxious, sad etc.), and also by
using the parameters of appropriateness, intensity, range, reactivity
and mobility. Affect may be described as appropriate or inappropriate to
the current situation, and as
congruent or
incongruent
with their thought content. For example, someone who shows a bland
affect when describing a very distressing experience would be described
as showing incongruent affect, which might suggest schizophrenia. The
intensity of the affect may be described as normal, blunted,
exaggerated, flat, heightened or overly dramatic. A flat or
blunted affect is associated with schizophrenia, depression or
post-traumatic stress disorder; heightened affect might suggest mania, and an overly dramatic or exaggerated affect might suggest certain
personality disorders.
Mobility refers to the extent to which affect changes during the
interview: the affect may be described as mobile, constricted, fixed,
immobile or
labile.
The person may show a full range of affect, in other words a wide range
of emotional expression during the assessment, or may be described as
having restricted affect. The affect may also be described as reactive,
in other words changing flexibly and appropriately with the flow of
conversation, or as unreactive. A bland lack of concern for one's
disability may be described as showing
belle indifférence,
[27] a feature of
conversion disorder, which is historically termed "
hysteria" in older texts.
[28][29][30]
Speech
The patient's
speech
is assessed by observing the patient's spontaneous speech, and also by
using structured tests of specific language functions. This heading is
concerned with the production of speech rather than the
content
of speech, which is addressed under thought form and thought content
(see below). When observing the patient's spontaneous speech, the
interviewer will note and comment on
paralinguistic features such as the loudness, rhythm,
prosody,
intonation, pitch,
phonation,
articulation,
quantity, rate, spontaneity and latency of speech. A structured
assessment of speech includes an assessment of expressive language by
asking the patient to name objects, repeat short sentences, or produce
as many words as possible from a certain category in a set time. Simple
language tests form part of the
mini-mental state examination. In practice, the structured assessment of receptive and expressive language is often reported under Cognition (see
below).
[31]
Language assessment will allow the recognition of medical conditions presenting with
aphonia or
dysarthria, neurological conditions such as
stroke or
dementia presenting with
aphasia, and specific language disorders such as
stuttering,
cluttering or
mutism. People with autism or
Asperger syndrome may have abnormalities in paralinguistic and
pragmatic aspects of their speech.
Echolalia (repetition of another person's words) and
palilalia (repetition of the subject's own words) can be heard with patients with
autism, schizophrenia or
Alzheimer's disease. A person with schizophrenia might use
neologisms,
which are made-up words which have a specific meaning to the person
using them. Speech assessment also contributes to assessment of mood,
for example people with mania or
anxiety may have rapid, loud and
pressured speech; on the other hand
depressed patients will typically have a prolonged speech latency and speak in a slow, quiet and hesitant manner.
[32][33][34]
Thought process
Thought
process in the MSE refers to the quantity, tempo (rate of flow) and
form (or logical coherence) of thought. Thought process cannot be
directly observed but can only be described by the patient, or inferred
from a patient's speech. Regarding the tempo of thought, some people may
experience
flight of ideas,
when their thoughts are so rapid that their speech seems incoherent,
although a careful observer can discern a chain of poetic associations
in the patient's speech. Alternatively an individual may be described as
having retarded or inhibited thinking, in which thoughts seem to
progress slowly with few associations. Poverty of thought is a global
reduction in the quantity of thought and thought
perseveration
refers to a pattern where a person keeps returning to the same limited
set of ideas. A pattern of interruption or disorganization of thought
processes is broadly referred to as
formal thought disorder,
and might be described more specifically as thought blocking, fusion,
loosening of associations, tangential thinking, derailment of thought,
or knight's move thinking. Thought may be described as circumstantial
when a patient includes a great deal of irrelevant detail and makes
frequent diversions, but remains focused on the broad topic. Flight of
ideas is typical of mania. Conversely, patients with depression may have
retarded or inhibited thinking. Poverty of thought is one of the
negative symptoms of schizophrenia, and might also be a feature of severe depression or
dementia.
A patient with dementia might also experience thought perseveration.
Formal thought disorder is a common feature of schizophrenia.
Circumstantial thinking might be observed in
anxiety disorders or certain kinds of
personality disorders.
[35][36][37]
Thought content
A description of thought content would describe a patient's
delusions, overvalued ideas, obsessions,
phobias
and preoccupations. Abnormalities of thought content are established by
exploring individual's thoughts in an open-ended conversational manner
with regard to their intensity, salience, the emotions associated with
the thoughts, the extent to which the thoughts are experienced as one's
own and under one's control, and the degree of belief or conviction
associated with the thoughts.
[38][39][40]
A delusion can be defined as "a false, unshakeable idea or belief
which is out of keeping with the patient's educational, cultural and
social background ... held with extraordinary conviction and subjective
certainty",
[41] and is a core feature of
psychotic disorders. The patient's delusions may be described as persecutory or
paranoid delusions,
delusions of reference,
grandiose delusions,
erotomanic delusions,
delusional jealousy or
delusional misidentification. Delusions may be described as mood-
congruent (the delusional content in keeping with the mood), typical of manic or
depressive psychoses,
or mood-incongruent (delusional content not in keeping with the mood)
which are more typical of schizophrenia. Delusions of control, or
passivity experiences (in which the individual has the experience of the
mind or body being under the influence or control of some kind of
external force or agency), are typical of schizophrenia. Examples of
this include experiences of
thought withdrawal,
thought insertion,
thought broadcasting, and somatic passivity.
Schneiderian first rank symptoms
are a set of delusions and hallucinations which have been said to be
highly suggestive of a diagnosis of schizophrenia. Delusions of guilt,
delusions of poverty, and nihilistic delusions (belief that one has no
mind or is already dead) are typical of
depressive psychoses.
An overvalued idea is a false belief that is held with conviction but not with delusional intensity.
Hypochondriasis is an overvalued idea that one is suffering from an illness,
dysmorphophobia is an overvalued idea that a part of one's body is abnormal, and people with
anorexia nervosa may have an overvalued idea of being overweight.
An obsession is an "undesired, unpleasant, intrusive thought that cannot be suppressed through the patient's volition",
[42]
but unlike passivity experiences described above, they are not
experienced as imposed from outside the patient's mind. Obsessions are
typically intrusive thoughts of violence, injury, dirt or sex, or
obsessive
ruminations
on intellectual themes. A person can also describe obsessional doubt,
with intrusive worries about whether they have made the wrong decision,
or forgotten to do something, for example turn off the gas or lock the
house. In
obsessive-compulsive disorder,
the individual experiences obsessions with or without compulsions (a
sense of having to carry out certain ritualized and senseless actions
against their wishes).
A phobia is "a dread of an object or situation that does not in reality pose any threat",
[43]
and is distinct from a delusion in that the patient is aware that the
fear is irrational. A phobia is usually highly specific to certain
situations and will usually be reported by the patient rather than being
observed by the clinician in the assessment interview.
Preoccupations are thoughts which are not fixed, false or intrusive,
but have an undue prominence in the person's mind. Clinically
significant preoccupations would include
thoughts of suicide,
homicidal thoughts, suspicious or fearful beliefs associated with
certain personality disorders, depressive beliefs (for example that one
is unloved or a failure), or the
cognitive distortions
of anxiety and depression. The MSE contributes to clinical risk
assessment by including a thorough exploration of any suicidal or
hostile thought content. Assessment of suicide risk includes detailed
questioning about the nature of the person's suicidal thoughts, belief
about death, reasons for living, and whether the person has made any
specific plans to end his or her life.
[44]
Perceptions
A
perception in this context is any sensory experience, and the three broad types of perceptual disturbance are
hallucinations,
pseudohallucinations and
illusions.
A hallucination is defined as a sensory perception in the absence of
any external stimulus, and is experienced in external or objective space
(i.e. experienced by the subject as real). An illusion is defined as a
false sensory perception in the presence of an external stimulus, in
other words a distortion of a sensory experience, and may be recognized
as such by the subject. A pseudohallucination is experienced in internal
or subjective space (for example as "voices in my head") and is
regarded as akin to fantasy. Other sensory abnormalities include a
distortion of the patient's sense of time, for example
déjà vu, or a distortion of the sense of self (
depersonalization) or sense of reality (
derealization).
Hallucinations can occur in any of the five senses, although
auditory and
visual hallucinations are encountered more frequently than
tactile (touch),
olfactory (smell) or
gustatory (taste) hallucinations. Auditory hallucinations are typical of
psychoses: third-person hallucinations (i.e. voices talking about the patient) and hearing one's thoughts spoken aloud (
gedankenlautwerden or
écho de la pensée) are among the
Schneiderian first rank symptoms
indicative of schizophrenia, whereas second-person hallucinations
(voices talking to the patient) threatening or insulting or telling them
to commit suicide, may be a feature of
psychotic depression or schizophrenia. Visual hallucinations are generally suggestive of organic conditions such as
epilepsy,
drug intoxication or drug withdrawal. Many of the visual effects of
hallucinogenic drugs
are more correctly described as visual illusions or visual
pseudohallucinations, as they are distortions of sensory experiences,
and are not experienced as existing in objective reality. Auditory
pseudohallucinations are suggestive of
dissociative disorders. Déjà vu, derealization and depersonalization are associated with
temporal lobe epilepsy and dissociative disorders.
[45][46]
Cognition
This section of the MSE covers the patient's level of
alertness,
orientation,
attention,
memory, visuospatial functioning,
language functions and
executive functions.
Unlike other sections of the MSE, use is made of structured tests in
addition to unstructured observation. Alertness is a global observation
of
level of consciousness
i.e. awareness of, and responsiveness to the environment, and this
might be described as alert, clouded, drowsy, or stuporose. Orientation
is assessed by asking the patient where he or she is (for example what
building, town and state) and what time it is (time, day, date).
Attention and concentration are assessed by the
serial sevens test (or alternatively by spelling a five-letter word backwards), and by testing
digit span.
Memory is assessed in terms of immediate registration (repeating a set
of words), short-term memory (recalling the set of words after an
interval, or recalling a short paragraph), and long-term memory
(recollection of well known historical or geographical facts).
Visuospatial functioning can be assessed by the ability to copy a
diagram, draw a clock face, or draw a map of the consulting room.
Language is assessed through the ability to name objects, repeat
phrases, and by observing the individual's spontaneous speech and
response to instructions. Executive functioning can be screened for by
asking the "similarities" questions ("what do x and y have in common?")
and by means of a verbal fluency task (e.g. "list as many words as you
can starting with the letter F, in one minute"). The mini-mental state
examination is a simple structured cognitive assessment which is in
widespread use as a component of the MSE.
Mild impairment of attention and concentration may occur in any
mental illness
where people are anxious and distractible (including psychotic states),
but more extensive cognitive abnormalities are likely to indicate a
gross disturbance of
brain functioning such as delirium, dementia or
intoxication. Specific language abnormalities may be associated with pathology in
Wernicke's area or
Broca's area of the brain. In
Korsakoff's syndrome
there is dramatic memory impairment with relative preservation of other
cognitive functions. Visuospatial or constructional abnormalities here
may be associated with
parietal lobe pathology, and abnormalities in executive functioning tests may indicate
frontal lobe
pathology. This kind of brief cognitive testing is regarded as a
screening process only, and any abnormalities are more carefully
assessed using formal
neuropsychological testing.
[47]
The MSE may include a brief neuropsychiatric examination in some
situations. Frontal lobe pathology is suggested if the person cannot
repetitively execute a motor sequence (e.g. "paper-scissors-stone"). The
posterior columns
are assessed by the person's ability to feel the vibrations of a tuning
fork on the wrists and ankles. The parietal lobe can be assessed by the
person's ability to identify objects by touch alone and with eyes
closed. A
cerebellar
disorder may be present if the person cannot stand with arms extended,
feet touching and eyes closed without swaying (Romberg's sign); if there
is a tremor when the person reaches for an object; or if he or she is
unable to touch a fixed point, close the eyes and touch the same point
again. Pathology in the
basal ganglia
may be indicated by rigidity and resistance to movement of the limbs,
and by the presence of characteristic involuntary movements. A lesion in
the
posterior fossa
can be detected by asking the patient to roll his or her eyes upwards
(Perinaud's sign). Focal neurological signs such as these might reflect
the effects of some prescribed psychiatric medications, chronic drug or
alcohol use,
head injuries,
tumors or other brain disorders.
[48][49][50][51][52]
Insight
The person's understanding of his or her mental illness is evaluated
by exploring his or her explanatory account of the problem, and
understanding of the treatment options. In this context,
insight can be said to have three components: recognition that one has a mental illness,
compliance with treatment, and the ability to re-label unusual mental events (such as delusions and hallucinations) as pathological.
[53]
As insight is on a continuum, the clinician should not describe it as
simply present or absent, but should report the patient's explanatory
account descriptively.
[54]
Impaired insight is characteristic of
psychosis and dementia, and is an important consideration in treatment planning and in assessing the capacity to
consent to treatment.
[55]
Judgment
Judgment refers to the patient's capacity to make sound, reasoned and
responsible decisions. Traditionally, the MSE included the use of
standard hypothetical questions such as "what would you do if you found a
stamped, addressed envelope lying in the street?"; however contemporary
practice is to inquire about how the patient has responded or would
respond to real-life challenges and contingencies. Assessment would take
into account the individual's
executive system capacity in terms of impulsiveness,
social cognition, self-awareness and planning ability.
Impaired judgment is not specific to any diagnosis but may be a prominent feature of disorders affecting the
frontal lobe
of the brain. If a person's judgment is impaired due to mental illness,
there might be implications for the person's safety or the safety of
others.
[56]
Cultural considerations
There are potential problems when the MSE is applied in a
cross-cultural
context, when the clinician and patient are from different cultural
backgrounds. For example, the patient's culture might have different
norms for appearance, behavior and display of emotions. Culturally
normative spiritual and religious beliefs need to be distinguished from
delusions and hallucinations - without understanding may seem similar
though they have different roots. Cognitive assessment must also take
the patient's language and educational background into account.
Clinician's racial bias is another potential confounder.
[57][58]
Children
There are particular challenges in carrying out an MSE with young children and others with limited language such as people with
intellectual impairment.
The examiner would explore and clarify the individual's use of words to
describe mood, thought content or perceptions, as words may be used
idiosyncratically
with a different meaning from that assumed by the examiner. In this
group, tools such as play materials, puppets, art materials or diagrams
(for instance with multiple choices of facial expressions depicting
emotions) may be used to facilitate recall and explanation of
experiences.